Approach to Appetite and Blood Sugar Control

Why can persons who are unsuccessful dieters, insulin resistant or who suffer from diabetes benefit from WeIIBetX PGX Simply, because PGX provides a whole new approach to using dietary polysaccharides, which are exceptionally effective at lessening hunger, reducing cholesterol levels, promoting regularity and healthy blood sugar balance. The addition of these fibers substantially improves daily intake of dietary fiber. PGX (short for PolyGlycoPlex) is the result of intense scientific development at the University of Toronto led by Vladimir Vuksan, Ph.D., one of the most respected and recognized experts on the role of diet in the risk of diabetes, heart disease and obesity. Soluble Fiber: How it works Many plants are rich in water-soluble fiber. Glucomannan (from Konjac root), psyllium, guar gum, defatted fenugreek seed powder, and pectin all provide fiber. Familiar seaweeds provide fiber such as alginate and carrageenan. Such sources of fiber are associated with reducing after-meal blood sugar levels, lowering cholesterol levels and promoting weight loss. When taken with water before meals these fiber sources bind to the water in the stomach and small intestine to form a gelatinous, viscous mass that not only slows down the absorption of glucose, but also induces a sense of satiety (fullness) and reduces the absorption of calories. In some of the clinical studies demonstrating weight loss, fiber supplements were shown to reduce the number of calories absorbed by 30 to 180 calories per day. While modest, this reduction in calories would, over the course of a year, result in a 3-to 18- pound weight loss. Dietary fiber supplements appear to exert a dose-dependent effect in lowering cholesterol and blood glucose levels as well as body weight. To achieve the greatest benefit, the dosage required (e.g. 20 grams or more) could be difficult to take. That problem has been over come by the development of PGX - a unique blend of selected, highly viscous soluble fibers that act synergistically to develop a higher level of viscosity and expansion with water than with the same quantity of any fiber alone. The synergistic effect of this unique blend means that PGXTM exerts an effect equal to 3 to 5 times as much as other fibers alone.

Why PGX works better!

PGX possesses the greatest viscosity (gelling property) of any single dietary fiber presently available because it uses a form of glucomannan that is highly refined and uniquely processed. It is 3-times as viscous as guar and approximately seven times as viscous as psyllium. By combining glucomannan with other soluble fibers, the viscosity of PGX is amplified further and has a viscosity 3-5 times higher than glucomannan alone. Clinical studies conducted by Dr. Vuksan have repeatedly shown that after-meal blood sugar levels decrease as soluble fiber viscosity increases. This relationship has also been shown to hold true for the other physiological benefits produced by soluble fibers including increased insulin sensitivity, diminished appetite, significant weight control, improved bowel movements and decreased serum cholesterol. PGX lowers postprandial (after meal) blood glucose by approximately 20% and also lowers insulin secretion by approximately 40% producing a whole body insulin sensitivity index improvement of nearly 50% - a phenomenal accomplishment that is unequalled by any drug or natural health product. Add to that its impressive effects on lowering blood cholesterol and triglyceride levels as well as its excellent safety profile and it is little wonder that we consider PGX a real superstar in the stable of natural products for diabetes. On top of that, University of Toronto researchers have recently found that higher doses of PGX can diminish appetite to such an extent that even the heaviest individuals have a dramatic and sustainable reduction in appetite. Why Mulberry? PGX capsules also contain a special extract of mulberry leaves. The Mulberry plant (Morus indica) is probably best known as the food for silkworms, but it is also highly regarded in traditional Chinese and Japanese medicine. Starches, complex carbohydrates, and even simple sugars like sucrose are broken down in the digestive tract into glucose by the action of certain enzymes. The most important enzymes are the alpha-glucosidases that line the intestines, essential for the breakdown of starches, complex carbohydrates, maltose, and sucrose into absorbable glucose molecules. Mulberry blocks the enzyme alpha glucodase. By inhibiting such enzymes, Mulberry extract diminishes after-meal rises in both glucose and insulin levels. Mulberry extract has been studied in type 2 diabetes and the results are excellent. In one study, researchers decided to investigate its effect on blood and red blood cell lipids as well as compare its blood sugar- lowering actions to the oral antihyperglycemic drug glyburide. Patients were given either mulberry dried leaves (3g/day) or one tablet of glyburide (5 mg/day) for 4 weeks. Mulberry therapy significantly improved diabetic control in type 2 diabetic patients. The results clearly show that the fasting blood glucose concentrations were significantly lowered with mulberry therapy, suggesting that mulberry therapy is effective in controlling diabetes. Compared to glyburide treatment, mulberry therapy reduced fasting blood glucose concentrations of diabetic patients by 27 percent. However, no significant differences were observed in blood glucose concentrations between pre- and post- treatments with glyburide. Mulberry extract was also superior to glyburide in its ability to decrease hemoglobin A values (a test that reveals up how much glucose has been sticking to hemoglobin molecules during the past 3-4 months), cholesterol, LDL, and triglycerides. It also results in an increase in HDL (good cholesterol). Although this change was not statistically significant, overall there are strong suggestions that this natural supplement is clearly superior to an established pharmaceutical agent.

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How will my body adjust?

PGX also results in fewer gastrointestinal side-effects than other viscous dietary fibers. This is because water-soluble fibers are fermented by intestinal bacteria, often resulting in gas being produced, leading to increased flatulence and abdominal discomfort. Generally the digestive system adapts to fiber over a few days and intestinal gas will become negligible. PGXTM minimizes that concern because it can be given in much smaller quantities than other viscous dietary fibers. to achieve comparable health benefits.

Easier Weight Control with PGX

As PGX absorbs hundreds of times its weight in water over 1 to 2 hours, it expands in the digestive tract creating a highly viscous (thick) gelatinous material. Once hydrated, this complex creates a lasting sense of fullness and it greatly stabilizes blood sugar and appetite hormones. Thus an adequate serving of PGXTM should make cutting calories much easier. For those who want to lose weight (using either a carbohydrate- or calorie-restricted diet), PGX provides effective weight management without suffering from hunger pangs.

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