Glucosamine Chondroitin: Structural Support for Joints
Glucosamine, which is synthesized in our bodies from
glucose, is a major component of joint-soothing glycosaminoglycans
(GAG's). Chondroitin sulfate is the most abundant GAG in the body.
GAG's in turn form proteoglycans, molecules that hold and bind the
water that is so important to lubricate joints, disperse stress and
provide nourishment to joint tissue. Glucosamine
sulfate has been found to be well-absorbed after oral administration.
Numerous double-blind, placebo-controlled studies have examined the
positive effects of oral administration of 1,500 mg of glucosamine
sulfate - the amount in one daily use of Glucosamine Chondroitin Complex with MSM.
Dietary Sulfur for Joint Lubrication
Both glucosamine sulfate and chondroitin sulfate
provide an additional source of sulfur, a mineral that is important for
healthy connective tissue. The formula also features MSM, or
methylsulfonylmethane, a naturally occurring form of organic sulfur
found in the body fluids and tissue, cow's milk, plants and most
natural foods. MSM is an important source of
dietary sulfur, which is vital to all tissues and needed constantly in
an assimilable form. Sulfur may promote joint flexibility due to its
role in supporting joint lubrication and movement.
Molybdenum: Critical Trace Mineral
Glucosamine Chondroitin Complex with MSM
also contains molybdenum to ensure an adequate supply of this trace
mineral to the body. High amounts of organic sulfur in the diet
increase urinary molybdenum loss. Molybdenum is necessary for the
proper functioning of the sulfite oxidase enzyme, which in turn
supports the proper metabolism of glucosamine sulfate and MSM.
Vitamin C: Essential for Collagen
Vitamin C is essential for the production and
stability of collagen, the major protein in cartilage and connective
tissue. It also protects cells from harmful free radicals.
Source: Source Naturals
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Scientific References
Conte, A. et. al. (1995). Arzneim. Forsch. Drug Research, 45(II):8, 918-925. Dovanti, A. et al. (1980). Clinical Therapeutics 3(4):266-72. Mazieres, B. et al. (1992). Rev. Rhum. Mal. Osteoartic. 59 (7-8), 466-472. Pipitone, V.R. (1991). Drugs Exptl. Clin. Res. XVII (1), 3-7. Rovetta, G. (1991). Drugs Exptl. Clin. Res. XVII (1), 53-57. Soldani, G. & Romagnoli J. (1991). Drugs Exptl. Clin. Res. XVII (1), 81-85. Tapadinhas, M.J. et al. (1982). Pharmatherapeutica 3(3): 157-68.
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